Methods: All patients underwent standard clinical assessment and

Methods: All patients underwent standard clinical assessment and pleural investigations in line with recent national guidelines and were followed up for a minimum of 1 year or until histological/microbiological diagnosis. Results: One hundred and fifty patients were recruited, and of these, 141 had a CTPA. PEs were

detected in 9/141 (6.4%) patients, and of these, 8/9 were subsequently diagnosed with pleural malignancy. In only 1 case was PE clinically suspected and in no case was PE the primary cause of effusion; 9.8% (8/82) of patients who were ultimately diagnosed with pleural malignancy had PE at presentation. Conclusions: This study indicates that PE is a frequent concomitant finding in patients with malignant effusions but uncommon as Repotrectinib clinical trial a primary cause of unilateral effusion. In addition, it highlights the known difficulty of clinical diagnosis of PE in the context of malignancy. In view of this, we recommend that CTPA combined CDK inhibitors in clinical trials with pleural-phase thoracic CT should be considered at presentation when investigating patients with suspected malignant pleural effusion. Copyright (C) 2013 S. Karger AG, Basel”
“We present the technique of anterior

thigh flap extended external hemipelvectomy with spinoiliac arthrodesis in treatment of the patient with recurrent low-grade pelvic chondrosarcoma extending to the lower lumbar spine. Extended hemipelvectomy

involves skeletal resection beyond the standard hemipelvectomy that is the SI joint by removal of contiguous musculoskeletal structures, such as elements of the sacral and lumbar spine or contralateral pelvic bone, in addition to the affected innominate bone. Spinoiliac arthrodesis reestablishes spinopelvic stability; the anterior thigh musculocutaneous flap provides reliable well-vascularized soft tissue coverage. This technique may serve an important role in the surgical management of patients with low-grade pelvic malignancies. (C) 2011 Elsevier Ltd. All rights reserved.”
“The effects of N vacancies on the transition metal (Cr, Mn, Fe, Co, Ni, and Cu) doped GaN have been studied at the levels of the local spin density approximation (LSDA) selleck compound and LSDA+U (Coulomb interaction). Our calculations show that the N vacancy favorably exists near a transition metal ion and the interaction between transition metal ion and N vacancy is insensitive to the distance when exceeding 3.3 A. Furthermore, we find that the existed N vacancies alter the magnetic moments of the doped GaN, where the magnetic moments increase for Cr or Mn doped GaN, and decrease for Fe, Co, Ni, or Cu doped GaN. This result can be interpreted well by the Hund’s multiplicity rules.

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