Techniques A multi-stage random sampling method had been utilized to choose the investigation things. Univariate analysis and logistic regression design were used to explore the result of social capital on standard of living on the list of old and senior rural-to-urban urbanized residents. Results The ratings of self-rated physical health insurance and psychological state in the rural-to-urban residents had been lower than those of urban residents ( P less then 0.05). The total rating of community personal money, neighborhood participation and neighborhood cohesion when you look at the rural-to-urban residents had been lower than those of metropolitan residents ( P less then 0.05). Caused by multivariate analysis showed that neighborhood attachment and community cohesion had been the defensive factors of actual health ( P less then 0.05), and community cohesion had been the safety element of mental health ( P less then 0.05). Conclusion There is a correlation between neighborhood belonging, neighborhood cohesion and total well being on the list of senior rural-to-urban residents. Interest is compensated to your advertising of community social capital so as to improve the wellness condition of middle-aged and elderly rural-to-urban residents. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective This study ended up being designed to research Biolog phenotypic profiling the effects of low focus hydrogen inhalation on asthma and rest function in mice as well as the possible method. Practices In the symptoms of asthma experiment, BALB/c mice had been randomly divided in to normal control team, asthma model group and hydrogen therapy team. After setting up ovalbumin (OVA)-induced asthma model, the hydrogen therapy team mice were treated by breathing of hydrogen (24-26 mL/L per day) for 7 successive days, therefore the typical control group and symptoms of asthma design group mice received similar treatment by inhalation of air. The amount of interleukin (IL)-4, IL-13, and interferon-γ (IFN-γ) in bronchoalveolar lavage fluid (BALF) were measured by commercially readily available ELISA kits. The amount of malondialdehyde (MDA) and glutathione (GSH), as well as the task YD23 of superoxide dismutase (SOD) in lung tissue were recognized by colorimetric assays. The pathological changes in lung structure were considered by HE staining. In the rest research, ICR mice had been randomly divided into empty control group and 1 d, 3 d, 5 d hydrogen treatment groups and diazepam group. The results of breathing of 24-26 mL/L a day hydrogen on the sleep duration induced by intraperitoneal injection of upper-threshold dose of sodium pentobarbital and the rest latency in response to subthreshold dosage had been examined. Results In the asthma research, the symptoms of asthma model team showed higher levels of IL-4 and IL-13 ( P0.05), that has been notably lower than compared to the diazepam group ( P less then 0.05). Conclusion Low concentration hydrogen inhalation could alleviate OVA-induced symptoms of asthma in mice, in addition to process might be regarding the anti-oxidative and anti-inflammatory ramifications of hydrogen. Additionally, reduced concentration hydrogen inhalation could improve rest purpose in mice. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).Objective This study was aimed to evaluate systems fundamental continuous training induced atrial fibrillation (AF) in an animal model. Methods Healthy New Zealand rabbits were split into three groups ( n=12 each) control group (C), moderate strength team (M), and high intensity team (H). The strength of continuous instruction chemical disinfection was adjusted based on the treadmill speed. After 12 days of instruction, with a Langendorff perfusion system, AF ended up being caused by S1S2 stimulation while the occurrence was recorded. Changes in atrial kir2.1, kir2.2, type Ⅰ and Ⅲ collagen protein mRNA expressions had been assessed by quantitative real-time PCR. Masson staining had been used to assess the extracellular collagen amount small fraction (CVF) . Outcomes After 12 months, researching with group C, groups M and H had greater ( P less then 0.05) CVF, occurrence of AF ( P less then 0.05, additionally between Groups H and M), and atrial inward rectifier potassium current/channel (IK 1) . In Group H, kir2.1, kir2.2, type Ⅰ and Ⅲ collagen protein mRNA expressions when you look at the remaining atrium had been increased ( P less then 0.05, compared to Groups C and M). Conclusion Long-term and high-intensity treadmill working could boost AF incidence in rabbits. Copyright© by Editorial Board of Journal of Sichuan University (healthcare Science Edition).Objective to see the changes of cardiac purpose in arthritic rats additionally the effectation of triptolide on it. Practices Forty rats were split in arbitrary into normal control (NC) group, model control (MC) group, leflunomide (LEF) team and triptolide (TP) group. Aside from the conventional group, rats within the other three teams had been inserted with Freund’s complete adjuvant to generate arthritic infection when you look at the right hind paws, plus the interventional medication ended up being administered in the 12th day after the irritation. By managing for 30 d, the cardiac purpose of rats was detected by left ventricular catheterization. The expressions of superoxide dismutase (SOD), malondialdehyde (MDA), reacitve oxygen species (ROS), total antioxidation (T-AOC), interleukin-10 (IL-10) and tumefaction necrosis factor-α (TNF-α) in serum had been measured by enzyme-linked immunosorbent assay. The expressions of keap-like necessary protein 1 ( Keap1), muscular aponeurotic fibrosarcom ( maf) and nuclear factor-E2 related factor2 ( Nrf2) mRNAs in cardiac structure had been dets and proteins in the heart cells regarding the triptolide group had been reduced ( P less then 0.01). Conclusion Triptolide could improve cardiac purpose in arthritic rats, while the mechanism may linked to its ability of improving the anti-oxidationin cardiomyocytes, reducing oxidative anxiety damage, and inhibiting abnormal immune inflammatory reaction.