thesAin sensitivity to 6 thioguanine. Overall, these results suggest that 6 thioguanine can be effective in the Abbot Maintenance and AG-490 enhanced resistant tumors BRCA1 or BRCA2-defective. The selection of patients for testing PARPi one big s challenge is to pr Predictive marker for therapy PARPi sporadic cancers, due to errors in the way of HR benefits Nnte be k. Several surrogate markers have been described, none of which widely used in clinical settings to today. Gene expression arrays for their pr Diktiven value were examined. Turner and his colleagues. Hypothesized that gene and protein expression signatures k Can the F Ability to identify the profile ness BRCA patients Konstantinopoulos and his colleagues have developed a profile as the BRCA gene expression correlates with PARPi and platinum sensitivity. Phosphorylation of Ser 139 residue of histone H2AX is variant forming gH2AX early cellular Re response to the induction of DNA CBD.
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